In the modern world, individuals are worried about their health because lifestyles have changed dramatically due to longer workdays and a lot of psychological pressures, which have increased the prevalence of many serious illnesses. Moreover, they disapprove of the costly, high-tech method of disease management and treatment. People have increasingly been interested in using phytonutrients and nutraceuticals for a range of medical applications since a few years ago. In addition to treating or preventing hypertension, high cholesterol, excessive blood sugar, degeneration, cataracts, menopausal symptoms, insomnia, poor memory and concentration, digestive issues, osteoporosis, arthritis, macular degeneration, and constipation, nutraceutical products also reduce the risk of cancer, heart disease, and other related conditions. Micronized food items and other nutraceutical supplements with enhanced health advantages are also produced thanks to nanotechnology. The most recent important discoveries (clinical research) on nutraceuticals that demonstrate their therapeutic effect on a range of diseases have been included in this review article.